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Cucurbituril-based dosage forms: a new macrocycle delivery vehicle to rival cyclodextrin

  • In: SUBMITTED ORALS on Tuesday, 15 April 2014, 16:00-17:30
  • At: PSWC, Melbourne (Australia) (2014)
  • Type: Presentation
  • By: WHEATE, Nial (The University of Sydney, Faculty of Pharmacy, Sydney, Australia)
  • Abstract:

    Background
    Cucurbit[n]urils are a family of macrocycles and the homologues CB[6], CB[7] and CB[8] are able to bind a range of small molecule and peptide based drugs within their cavity. Cucurbiturils are superior to cyclodextrins with lower toxicity and a range of drug benefits including: improved chemical/physical stability, water solubility,..

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Last update 28 September 2023

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