Effect on pvp / tadalafil solid dispersion prepared using supercritical anti-solvent method with operating parameters

• In: Poster presentation
• At: Seoul (South Korea) (2017)
• Type: Poster
• Poster code: POS-FDP-009
• By: HAM, Gun Joo (Korea, Republic Of)
• Co-author(s): Gun Joo Ham: College of pharmacy, Yonsei university, Incheon, Korea, Republic Of
  In Taek Shin: College of pharmacy, Yonsei university, Incheon, Korea, Republic Of
  Sung-Joo Hwang: College of pharmacy, Yonsei university, Incheon, Korea, Republic Of
  
• Abstract:

  Background

  Various parameters effect Supercritical anti-solvent (SAS) process, which was utilized to produce tadalafil solid dispersion submicron particles.

  Purpose

  The purpose of this study is determining patterns of SAS processing parameters (temperature, pressure, and drug concentration) that could improve dissolution rate.

  Methods

  The SAS process..

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