Atherosclerosis is exacerbated by chitinase-3-like-1 in an amyloid precursor protein transgenic mice

• In: Poster presentation
• At: Seoul (South Korea) (2017)
• Type: Poster
• Poster code: POS-TRI-005
• By: SON, Dong Ju (Chungbuk National University, College of Pharmacy, Cheongju, Korea, Republic Of)
• Co-author(s): Dong Ju Son:
  Young Sik Seo: Department of Molecular Biology and Institute of Nanosensor Biotechnology, Dankook University, Yongin, Korea, Republic Of
  Heonyong Park: Department of Molecular Biology and Institute of Nanosensor Biotechnology, Dankook University, Yongin, Korea, Republic Of
  Dae Youn Hwang: College of Natural Resources & Life Science, Pusan National University, Miryang, Korea, Republic Of
  Sang Bae Han: College of Pharmacy, Chungbuk National University, Cheongju, Korea, Republic Of
  Sanghyeon Kim: Stanley Brain Research Laboratory, Stanley Medical Research Institute, Rockville, United States
  Jin Tae Hong: College of Pharmacy, Chungbuk National University, Cheongju, Korea, Republic Of
  
• Abstract:

  Background

  Although the critical role of amyloid precursor protein (APP) on vascular diseases associated with Alzheimer’s disease (AD) has been demonstrated, the underlying molecular mechanisms and physiological consequences are unclear. 

  Purpose

  We aimed to evaluate vascular inflammation and atherosclerosis in Swedish mutant of human APP transgenic..

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