Solubilisation of ibuprofen in mixed-surfactant systems containing poloxamer 407 and selected polioxyethylene-derivative surfactants

• In: Poster presentation
• At: Seoul (South Korea) (2017)
• Type: Poster
• Poster code: POS-FDP-024
• By: PLUTA, Janusz (Polish Pharmaceutical Society, Department of Drug Form Technology, Warsaw, Poland)
• Co-author(s): Janusz Pluta: Department of Drug Form Technology, Faculty of Pharmacy, Wroclaw Medical University, Wrocław, Poland;Department of Pharmacology, Opole Medical School (PMWSZ), Opole, Poland
  Kamil P Grela: Department of Drug Form Technology, Faculty of Pharmacy, Wroclaw Medical University, Wrocław, Poland
  Dominik M Marciniak: Department of Drug Form Technology, Faculty of Pharmacy, Wroclaw Medical University, Wrocław, Poland
  Anna Cap:
  Jakub Burak: Department of Drug Form Technology, Faculty of Pharmacy, Wroclaw Medical University, Wrocław, Poland
  
• Abstract:

  Background

  The nonionic surfactant poloxamer 407 (P407) is known as a gel-forming excipient, but also as an efficient solubiliser for some lipophilic substances.

  Purpose

  The aim of this study was to measure the influence of chosen polyoxyethylene-derivative surfactants (PEX) on the solubility of ibuprofen (IBU) in thermogelling P407 solutions at..

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