Development and evaluation of lyophilized orally disintegrating tablets containing metformin hydrochloride and glyburide

• In: Poster presentation
• At: Seoul (South Korea) (2017)
• Type: Poster
• Poster code: POS-FDP-002
• By: AKDAG CAYLI, Yagmur (Hacettepe University, Pharmaceutical Technology, Turkey)
• Co-author(s): Yagmur Akdag Cayli:
  Tugba Gulsun: Pharmaceutical Technology, Hacettepe University, Ankara, Turkey
  Nihan Izat: Pharmaceutical Technology, Hacettepe University, Ankara, Turkey
  Meltem Cetin: Pharmaceutical Technology, Atatürk University, Erzurum, Turkey
  Levent Oner: Pharmaceutical Technology, Hacettepe University, Ankara, Turkey
  Selma Sahin: Pharmaceutical Technology, Hacettepe University, Ankara, Turkey
  
• Abstract:

  Background

  Metformin hydrochloride (MH) and glyburide (GB) are oral antidiabetic agents which can be combined to treat Type 2 diabetes. To our knowledge, there is no commercially available orally disintegrating tablets (ODTs) for this combination.

  Purpose

  The aim of this study was to develop and evaluate MH and GB containing ODT by freeze-drying..

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