Potential interaction of scutellariae radix on the pharmacokinetics and pharmacodynamics of metformin in rats

• In: Poster presentation
• At: Seoul (South Korea) (2017)
• Type: Poster
• Poster code: POS-PAA-006
• By: CHOI, Young Hee (Dongguk University, College of Pharmacy, Korea, Republic Of)
• Co-author(s): Young Hee Choi: College of Pharmacy, Dongguk University, Korea, Republic Of
  Byung Hoon You: College of Pharmacy, Dongguk University, Korea, Republic Of
  Young-Won Chin: College of Pharmacy, Dongguk University, Korea, Republic Of
  
• Abstract:

  Background

  Formerly metformin and Scutellariae Radix extract combination has been reported to enhance anti-diabetic activity.  Organic cation transporters and multi-drug and toxin extrusion proteins in liver and kidney are determinant factors on hepatic distribution and renal clearance of metformin.

  Purpose

  To predict the potential of interaction..

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