Screening of oxidative metabolism of flavonoid aglycones by liquid chromatography-mass spectrometry

• In: Poster presentation
• At: Seoul (South Korea) (2017)
• Type: Poster
• Poster code: POS-NPR-001
• By: BENKOVIC, Goran (Agency for Medicinal Products and Medical Devices, Zagreb, Croatia)
• Co-author(s): Goran Benković: Official Medicines Control Laboratory, Agency for Medicinal Products and Medical Devices, Zagreb, Croatia
  Rajka Truban Žulj: Official Medicines Control Laboratory, Agency for Medicinal Products and Medical Devices, Zagreb, Croatia
  Mirza Bojić: Department for Pharmaceutical Chemistry, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, Croatia
  
• Abstract:

  Background

  Cytochromes P450 are the most significant enzymes for drug metabolism. Flavonoids are common constituents of everyday diet that have been shown to have beneficial potential on human health. Flavonoids undergo substantial hepatic metabolism and the metabolites might significantly contribute to the effects of these dietary constituents as

  ..

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