Frequency of sterigmatocystin (stc)-producing dustborne aspergilli from flooded and unflooded houses in croatia – employment of hplc/dad/ms method in stc exposure assessment

• In: Poster presentation
• At: Seoul (South Korea) (2017)
• Type: Poster
• Poster code: POS-ASP-008
• By: SERTIć, Miranda (University of Zagreb Faculty of Pharmacy and Biochemistry, Department of analytics and control of medicines, Zagreb, Croatia)
• Co-author(s): Miranda Sertic: University of Zagreb Faculty of Pharmacy and Biochemistry, Zagreb, Croatia
  Daniela Jakšić Despot: University of Zagreb Faculty of Pharmacy and Biochemistry, Zagreb, Croatia
  Ana Mornar: University of Zagreb Faculty of Pharmacy and Biochemistry, Zagreb, Croatia
  Domagoj Kifer: University of Zagreb Faculty of Pharmacy and Biochemistry, Zagreb, Croatia
  Biljana Nigović: University of Zagreb Faculty of Pharmacy and Biochemistry, Zagreb, Croatia
  Maja Šegvić Klarić: University of Zagreb Faculty of Pharmacy and Biochemistry, Zagreb, Croatia
  
• Abstract:

  Background

  STC is precursor of aflatoxin and also the end product in biosynthesis of Aspergilli from the section Versicolores. Mechanism of STC toxicity is transformation by CYP monooxygenases into epoxide, which forms DNA-adducts leading to hepatotoxicity and carcinogenicity. STC-producing Aspergilli are frequently airborne in damp dwellings and

  ..

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