Lipoprotein association plays a critical role in promoting lymphatic transport of a biomimetic prodrug of mycophenolic acid
- In: Posters D - Formulation Design and Pharmaceutical Technology
- At: PSWC, Melbourne (Australia) (2014)
- Type: Poster
- Poster code: PD-049
- By: HAN, Sifei (Monash University, Drug Delivery, Disposition and Dynamics, Melbourne, Australia)
- Co-author(s): Hu, Luojuan (Monash University, Melbourne, Australia)
Quach, Tim (Monash University, Melbourne, Australia)
Simpson, Jamie (Monash University, Melbourne, Australia)
Trevaskis, Natalie (Monash University, Melbourne, Australia)
Porter, Christopher (Monash University, Melbourne, Australia) - Abstract:
Background
Following ingestion, dietary triglycerides (TG), are transported via the intestinal lymphatic system - in the form of enterocyte-assembled lipoproteins (LP). Inspired by this unique metabolic pathway, a TG mimetic prodrug (MPA-TG, Fig. 1) was conceived and demonstrated in our previous studies to markedly promote the delivery of.. The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.
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Last update 28 September 2023