Molecularly targeted dual drug loaded lipid-protein hybrid nanoparticles for synergistic combinational chemotherapy

• In: Poster presentation
• At: Seoul (South Korea) (2017)
• Type: Poster
• Poster code: POS-FDP-037
• By: YONG, Chul Soon (Yeungnam University, Gyeongsan-Si, Korea, Republic Of)
• Co-author(s): Jae Hee Kim: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
  Hima Bindu Ruttala: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
  Gyeong Jin An: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
  Myung-Ja Hong: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
  Jee-Heon Jeong: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
  Dong Shik Kim: Hanyang University, Ansan-si, Korea, Republic Of
  Han-Gon Choi: Hanyang University, Ansan-si, Korea, Republic Of
  Chul Soon Yong: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
  Jong Oh Kim: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
  
• Abstract:

  Background

  Abraxane® showed some potential limitations including hypersensitivity reactions importantly its poor colloidal stability, which results in a poor pharmacokinetic pattern in the systemic circulation.

  Purpose

  A transferrin-anchored albumin nanoplatform with PEGylated lipid bilayers(Tf-L-APVN) was developed for the targeted co-delivery of..

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