Surface modification of solid lipid nanoparticles for oral delivery of curcumin: improvement of bioavailability through enhanced cellular uptake, and lymphatic uptake

• In: Poster presentation
• At: Seoul (South Korea) (2017)
• Type: Poster
• Poster code: POS-FDP-004
• By: CHO, Cheong-Weon (Korea, Republic Of)
• Co-author(s): Young-Guk Na
  Jong-Suep Baek
  Cheong-Weon Cho
  
• Abstract:

  Background

  Curcumin has been reported to exhibit potent anticancer effects. However, poor solubility, bioavailability and stability of curcumin limit its in vivo efficacy for the cancer treatment. 

  Purpose

  The first objective of this study was to fabricate NCC-SLN for preventing burst release of curcumin in simulated gastric fluid and to evaluate..

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