Pharmacokinetics and anti-gastric ulceration activity of oral administration of aceclofenac and esomeprazole in rats

• In: Poster presentation
• At: Seoul (South Korea) (2017)
• Type: Poster
• Poster code: POS-PAA-017
• By: SHIN, Beom Soo (Catholic University of Daegu, College of Pharmacy, Gyeongsan-si, Korea, Republic Of)
• Co-author(s): Junwoo Park: School of Pharmacy, Sungkyunkwan University, Suwon, Korea, Republic Of
  Tae Hwan Kim: Center for Pharmacometrics and Systems Pharmacology, University of Florida, Orlando, United States
  Subindra Kazi Thapa: College of Pharmacy, Wonkwang University, Iksan, Korea, Republic Of
  Hyeon Myeong Jeong: College of Pharmacy, Wonkwang University, Iksan, Korea, Republic Of
  Seung Eun Cheung: College of Pharmacy, Catholic University of Daegu, Gyeongsan-si, Korea, Republic Of
  Da Young Lee: College of Pharmacy, Catholic University of Daegu, Gyeongsan-si, Korea, Republic Of
  Youn-Woong Choi: Korea United Pharm. Inc, Seoul, Korea, Republic Of
  Sang-Min Cho: Korea United Pharm. Inc, Seoul, Korea, Republic Of
  Kyu-Yeol Nam: Korea United Pharm. Inc, Seoul, Korea, Republic Of
  Won-Ho Kang: Korea United Pharm. Inc, Seoul, Korea, Republic Of
  Soyoung Shin: College of Pharmacy, Wonkwang University, Iksan, Korea, Republic Of
  Beom Soo Shin: College of Pharmacy, Catholic University of Daegu, Gyeongsan-si, Korea, Republic Of
  
• Abstract:

  Background

  "EN-US">Gastroprotective therapy using proton pump inhibitors such as esomeprazole in combination with nonsteroidal anti-inflammatory drugs (NSAIDs) has been recommended for the patients who have risk factors for gastrointestinal complications. One of the most popular NSAIDs, aceclofenac may have clinical benefits when combined with..

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