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Green tea elevated the blood level of indoxyl sulfate, a nephro - cardiovascular toxin, in renal failure rats

  • In: Posters G - Pharmacokinetics (PK), Pharmacodynamics (PD) and Systems Pharmacology
  • At: PSWC, Melbourne (Australia) (2014)
  • Type: Poster
  • Poster code: PG-019
  • By: PENG, Yu-Hsuan (China Medical University, School of Pharmacy, Taichung, China Taiwan)
  • Co-author(s): Lin, Shiuan-Pey (China Medical University, Taichung, China Taiwan)
    Shia, Chi-Sheng (China Medical University, Taichung, China Taiwan)
    Hou, Yu-Chi (China Medical University, Taichung, China Taiwan)
    Chao, Pei-Dawn Lee (China Medical University, Taichung, China Taiwan)
  • Abstract:

    I. Background
    Indoxyl sulfate (IS) is a highly protein-bound nephro-cardiovascular toxin, which cannot be removed via hemodialysis. The serum IS concentration was a predictor for the progression of renal and cardiovascular diseases as well as all-cause mortality. The transport of IS was associated with organic anion transporters (OATs) and breast..

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Last update 28 September 2023

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