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The science of extrapolation: In vitro and in vivo approaches

  • In: Symposium E3: Medicines for the real life population: the science of extrapolation on Tuesday, 23 May 2017, 15:05-15:35
  • At: Stockholm (Sweden) (2017)
  • Type: Presentation
  • By: ROSTAMI, Amin (University of Manchester, Manchester Pharmacy School, Manchester, United Kingdom)
  • Co-author(s): Amin Rostami: Manchester Pharmacy School, University of Manchester, Manchester, United Kingdom;, Certara, Princeton, United States
  • Abstract:

    The need for change from current practices in deriving dosing recommendation in specific populations has been highlighted recently (Jadhav et al 2015, Younis et al 2016). Currently, dose requirements in various co-morbidity conditions are assessed mainly through parallel studies or via statistical analysis of sparse samples taken from diverse


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Last update 28 September 2023

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