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Rapid intranasal delivery of metoclopramide hydrochloride: efficacy and safety of various absorption enhancers and pharmacokinetic evaluation

  • In: SIG Bioavailability / Bioequivalence - Poster Session
  • At: Cairo (Egypt) (2005)
  • Type: Poster
  • Poster code: BB-P-022
  • By: AWAD (Pharmacy Faculty AinShams University, Pharmaceutics, Cairo, Egypt)
  • Co-author(s): Abdel Hady (Pharmacy Faculty AinShams University, CAIRO, Egypt)
    Mortada, Nahed (Pharmacy Faculty AinShams University, CAIRO, Egypt)
    Zaki (Pharmacy Faculty AinShams University, CAIRO, Egypt)
  • Abstract:

    Aims: Evaluation of efficacy and safety of different absorption enhancers used in the preparation of nasal solution (NS) of metoclopramide hydrochloride (MPC HCl), and determination of pharmokinetics parameters of the drug in the formula containing the safest enhancer. Methods: Different enhancers viz: sodium deoxycholate (SDC), sodium cholate..

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Last update 28 September 2023

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