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Formulation and development of chitosan based in situ thermosensitive injectable hydrogel of pegylated melphalan conjugates

  • In: Posters: Formulation Design and Pharmaceutical Technology
  • At: Bangkok (Thailand) (2014)
  • Type: Poster
  • Poster code: POS-FDP038
  • By: SARAF, Shailendra (University Institute of Pharmacy, Pharmacy, Raipur, chhattisgarh, India)
  • Co-author(s): Saraf, Swarnlata (University Institute of Pharmacy, Raipur, chhattisgarh, India)
    Alexander, Amit (University Institute of Pharmacy, Raipur, chhattisgarh, India)
  • Abstract:

    To reduce the burst effect and to provide a controlled release, a blend of Chitosan(CS)/glycerophosphate disodium (GP) thermosensitive hydrogels were prepared for the sustained delivery of an alkylating agent, melphalan (ML).
    In the present study, poorly soluble alkylating drug, melphalan (ML) is PEGylated with linear methoxy poly ..

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Last update 28 September 2023

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