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Bioavailability of desmopressin from a superporous hydrogel based drug delivery system

  • In: Industrial Pharmacy Section - Poster Session
  • At: Cairo (Egypt) (2005)
  • Type: Poster
  • Poster code: IPS-P-002
  • By: POLNOK, Assadang (Faculty of Pharmaceutical Sciences, Pharmaceutical Technology, Phitsanulok, Thailand)
  • Co-author(s): Verhoef (Leiden University, LEIDEN, Netherlands)
    Sarisuta (Mahidol University, BANGKOK, Thailand)
    Peterson (Ferring Pharmaceutical, MALMÖ, Sweden)
    Leelamanit (Mahidol University, BANGKOK, Thailand)
    Junginger (Leiden University, LEIDEN, Netherlands)
  • Abstract:

    The purpose of this study was to evaluate the bioavailability of desmopressin formulated in a superporous hydrogel based drug delivery system without and with N-trimethyl chitosan (TMC), an absorption enhancer, in juvenile pigs.

    Six female pigs, average body weight of 30 kg, were operated to insert a silicone cannula at the jugular vein for blood ..

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Last update 28 September 2023

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