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Efficiency of gene delivery on hepatoma cells with polyplex and ternary complex

  • In: Hospital Pharmacy Section - Poster session
  • At: Cairo (Egypt) (2005)
  • Type: Poster
  • Poster code: HPS-P-021
  • By: SASAKI, Hitoshi (Nagasaki University Hospital, Department of Hospital Pharmacy, Nagasaki, Japan)
  • Co-author(s): Nakamura (Nagasaki University Hospital, NAGASAKI, Japan)
    Nakamura (Nagasaki University Hospital, NAGASAKI, Japan)
    Nakashima (Nagasaki University Hospital, NAGASAKI, Japan)
    Ichikawa (Nagasaki University Hospital, NAGASAKI, Japan)
    Nishida (Nagasaki University, NAGASAKI, Japan)
    Nakamura (Nagasaki University, NAGASAKI, Japan)
  • Abstract:

    Aimes: The aimes of this study is to investigate the efficiency of plasmid DNA (pDNA)/polyethylenimine (PEI) complex (polyplex) and pDNA/PEI/polyanion complex (ternary complex) as gene delivery vectors in a human hepatoma cell line HepG2.

    Methods: pDNA encoding luciferase gene was complexed with PEI at various charge ratios. It awa also..

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Last update 28 September 2023

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