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Determination of omeprazole, lanzoprazole and pantoprazole in presence of their acid- induced degradation products using derivative- ratio spectrophotometry and partial least squares methods.

  • In: SIG Quality of Pharmaceuticals - Poster Session
  • At: Cairo (Egypt) (2005)
  • Type: Poster
  • Poster code: QP-P-009
  • By: WAHBI, Abdelaziz (University of Alexandria, Pharm. Analytical Chemistry, Alexandria, Egypt)
  • Co-author(s): Fahmy (University of Alexandria, ALEXANDRIA, Egypt)
    Moneeb (University of Alexandria, ALEXANDRIA, Egypt)
  • Abstract:

    Omeprazole I, lansoprazole II, and pantoprazole III, have been determined trically in presence of their acid-induced degradation products using (i) first and second order-derivative ratios and (ii) PLS applied to absorbance and absorbance ratio data. Laboratory prepared mixtures of the intact compounds with the corresponding acid induced..

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Last update 28 September 2023

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