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Effect of cefepime on startle amplitude and prepulse inhibition of startle reflex in rats: manipulation of gaba-a receptor function with midazolam.

  • In: Academic Pharmacy Section - Poster Session
  • At: Cairo (Egypt) (2005)
  • Type: Poster
  • Poster code: AS-P-007
  • By: KHALIFA, AMANI (Faculty of Pharmacy Ain shams university, PHARMACOLOGY & TOXICOLOGY, Cairo, Egypt)
  • Abstract:

    Disruption of prepulse inhibition (PPI) of startle response is manifested in schizophrenia and Huntington’s disease among other neuropsychiatric disorders characterized by sensorimotor gating deficit. Antagonism of GABA(A) receptor function was documented to enhance PPI response. Nevertheless, contradicting reports suggest that GABA(A)..

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Last update 28 September 2023

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