The effect of sparkling water on intraluminal formulation behaviour and systemic drug performance in man
- In: Poster Presentation
- At: Stockholm (Sweden) (2017)
- Type: Poster
- Poster code: P-B-064-Tuesday
- By: VAN DEN ABEELE, Jens (KU Leuven, Drug Delivery and Disposition, Leuven, Belgium)
- Co-author(s): Jens Van Den Abeele: Drug Delivery and Disposition, KU Leuven, Leuven, Belgium
Joachim Brouwers: Drug Delivery and Disposition, KU Leuven, Leuven, Belgium
Jan Tack: Department of Gastroenterology, UZ Leuven, Leuven, Belgium
Patrick Augustijns: Drug Delivery and Disposition, KU Leuven, Leuven, Belgium - Abstract:
Backgrounds
In the fasted stomach, periods of contractile quiescence alternate periods of intense contractile activity. In daily practice, gastric contractile activity during drug intake is not known, possibly leading to marked intra- and inter-individual variability in dosage form disintegration, gastric drug emptying and subsequent systemic drug
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Last update 28 September 2023