Conjunctival drug permeability, employing QSPR and PK models
- In: Poster Presentation
- At: Stockholm (Sweden) (2017)
- Type: Poster
- Poster code: P-B-106-Tuesday
- By: RAMSAY, Eva (University of Eastern Finland, School of Pharmacy, Helsinki, Finland)
- Co-author(s): Eva Ramsay: School of Pharmacy, University of Eastern Finland, Kuopio, Finland;Faculty of Pharmacy, University of Helsinki, Helsinki, Finland
Theo Picardet: School of Pharmacy, University of Eastern Finland, Kuopio, Finland
Eva M. del Amo: School of Pharmacy, University of Eastern Finland, Kuopio, Finland
Unni Tengvall: School of Pharmacy, University of Eastern Finland, Kuopio, Finland
Seppo Auriola: School of Pharmacy, University of Eastern Finland, Kuopio, Finland
Elisa Toropainen: School of Pharmacy, University of Eastern Finland, Kuopio, Finland
Marika Ruponen: School of Pharmacy, University of Eastern Finland, Kuopio, Finland
Arto Urtti: School of Pharmacy, University of Eastern Finland, Kuopio, Finland;Faculty of Pharmacy, University of Helsinki, Helsinki, Finland - Abstract:
Backgrounds
Topical administration on the ocular surface is followed by large fraction of the dose to be absorbed across the conjunctiva to the systemic blood circulation, due to larger surface area and leakier membrane of the conjunctiva than that of cornea. However, systematic studies of conjunctiva as permeation barrier for small molecular drugs
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Last update 28 September 2023