Biorelevant tests combined with a Physiologically Based Pharmacokinetic Model predict the in vivo behaviour of Ciprofloxacin
- In: Poster Presentation
- At: Stockholm (Sweden) (2017)
- Type: Poster
- Poster code: P-C-028-Monday
- By: HANSMANN, Simone (Goethe University, Institute of Pharmaceutical Technology, Frankfurt, Germany)
- Co-author(s): Simone Hansmann: Institute of Pharmaceutical Technology, Goethe University, Frankfurt, Germany
Jennifer Dressman: Institute of Pharmaceutical Technology, Goethe University, Frankfurt, Germany - Abstract:
Backgrounds
Physiologically based Pharmacokinetic ModelsAims
The aim of this study was 1) to investigate the behaviour of ciprofloxacin, a BCS Class IV weakly basic drug, under conditions simulating the upper GI tract in humans using in vitro dissolution in single media, in a two-stage method and in transfer experiments and 2) to simulate the plasma
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Last update 28 September 2023