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Potassium channel related mechanisms of mpp+-induced cell death in wild type and alpha-synuclein-transfected sh-sy5y
- In: SIG Pharmaceutical Biotechnology - Posters
- At: Beijing (China) (2007)
- Type: Poster
- Poster code: PB-P-003
- By: SHI, Qiaoqiao (Institute of Materia Medica, Beijing, China)
- Co-author(s): Wang, Xiaoliang (Institute of Materia Medica, BEIJING, China)
- Abstract:
Aim: To investigate the mechanisms of the dopaminergic neurons death in Parkinson Disease (PD), we studied the roles of the potassium channel in MPP+-induced cell death in wild type and alpha-synuclein-transfected SH-SY5Y. Methods: Wild type (WT) and A53T mutant alpha-synuclein-transfected SH-SY5Y were exposed to MPP+ (1-methyl-4-phenylpyridinium) ..
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Last update 28 September 2023