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First synthesisof 12-oxosoladucidine and its derivatives as potential anti-tumor steroidal alkaloids
- In: SIG Natural Substances - Posters
- At: Beijing (China) (2007)
- Type: Poster
- Poster code: NS-P-056
- By: ZHA, Xiaoming (China Pharmaceutical University, Nanjing, China)
- Co-author(s): Hou, Yingwei (China Pharmaceutical University, NANJING, China)
Sun, Hongbin (China Pharmaceutical University, NANJING, China)
Zhang, Yihua (China Pharmaceutical University, NANJING, China) - Abstract:
First synthesis of 12-oxosoladucidine 4 and its derivatives as potential anti-tumor steroidal alkaloids is described. Starting from hecogenin 5, 4 was prepared in five steps with overall yield 31%. Moreover, 8 derivatives of 4 were synthesized. First synthesis of 12-oxosoladucidine 4 and its derivatives as potential anti-tumor steroidal alkaloids..
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Last update 28 September 2023