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A model-based comparison of absorption pharmacokinetics for a selective glucocorticoid receptor modulator administered with different inhalation devices
- In: Poster Presentation
- At: Stockholm (Sweden) (2017)
- Type: Poster
- Poster code: P-A-097-Monday
- By: SADIQ, Muhammad Waqas (AstraZeneca, Quantitative Clinical Pharmacology, Mölndal, Sweden)
- Co-author(s): Muhammad Waqas Sadiq: Quantitative Clinical Pharmacology (ECD), AstraZeneca R&D, Gothenburg, Sweden
Åsa Kragh: Quantitative Clinical Pharmacology (ECD), AstraZeneca R&D, Gothenburg, Sweden
Susanne Prothon: Quantitative Clinical Pharmacology (ECD), AstraZeneca R&D, Gothenburg, Sweden
Yingxue Chen: Quantitative Clinical Pharmacology (ECD), AstraZeneca R&D, Gothenburg, Sweden
Ajay Aggarwal: Early Clinical development, AstraZeneca R&D, Waltham, United States
Ulrika Wahlby-Hamren: Quantitative Clinical Pharmacology (ECD), AstraZeneca R&D, Gothenburg, Sweden - Abstract:
Backgrounds
AZD7594 is non-steroidal selective inhaled glucocorticoid receptor modulator (iSGRM) currently in development for the treatment of asthma.Aims
This work presents population pharmacokinetic (PK) modelling performed to quantify the absorption PK after inhaled administration of AZD7594 with different devices.Methods
Data from a phase 1
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Last update 28 September 2023