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Pharmacological Characterization of Novel Taxus Lignans as Potent Inhibitors for the Initial Stage of Neurodegrative Diseases
- In: SIG Posters
- At: Amsterdam (the Netherlands) (2012)
- Type: Poster
- Poster code: NPR-P-28
- By: OHTSUKI, Kenzo (Kitasato University, Molecular Signal Biology, Med. Sci., Sagamihara, Japan)
- Co-author(s): Okano, T.O. (Kitasato University, Sagamihara, Japan)
- Abstract:
..
I. Background
Recently, several novel lignans were identified from
Taxus yunnanensis
, and demonstrated to exhibit their anti-inflammatory and neuroprotective effects. By the
in vitro
assay using three functional brain proteins [MBP, TP (tau protein) and CAMP-2] for GSK-3ß, three
Taxus
lignans (A, C and E) were selected as effective mediators for The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.
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Last update 28 September 2023