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Matrine attenuates nonalcoholic fatty liver diseases through inhibition serca2c
- At: Glasgow (Scotland) (2018)
- Type: Poster
- Poster code: POS-NPR-025
- By: ZHANG, Yan (Tangdu Hospital, Fourth Military Medical Universit, Department of Pharmacy,)
- Co-author(s): Yan Zhang
Lei Shi: Department of Pharmacy, Tangdu Hospital, Fourth Military Medical University, xi'an, China
Song Zhang: Department of Pharmacy, Tangdu Hospital, Fourth Military Medical University, Xi'an, China
Shun Guo: Department of Pharmacy, Tangdu Hospital, Fourth Military Medical University, Xi'an, China
Xiaobo Gao: Department of Pharmacy, Tangdu Hospital, Fourth Military Medical University, Xi'an, China - Abstract:
Background
The histological spectrum of nonalcoholic fatty liver diseases (NAFLD) ranges from hepatic steatosis to steatohepatitis. Redistribution of intracellular calcium from the endoplasmic reticulum (ER) to the mitochondria can lead to ER stress, induce mitochondrial dysfunction, and accelerate the development of NAFLD to steatohepatitisMethods
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Last update 28 September 2023